Federal R&D Expenditures and the Geographic Concentration of R&D Activity

RD-flatness and RD-injectivity

It is proved that every commutative ring whose RD-injective modules are Σ-RD-injective is the product of a pure semi-simple ring and a finite ring. A complete characterization of commutative rings for which each artinian (respectively simple) module is RD-injective, is given. These results can be obtained by using the properties of RD-flat modules and RD-coflat modules which are respectively th...

Early markers of retinal degeneration in rd/rd mice.

PURPOSE In the rd/rd mouse, the cell death of rod photoreceptors has been correlated to abnormal levels of the cyclic nucleotide cGMP within photoreceptors. Given that cGMP is required for opening of the cationic channels, there is the possibility that a high cGMP concentration would maintain these channels open, at a high energy cost for the retina. METHODS We investigated whether cation cha...

Proceedings of the 3 rd

Morphological and functional abnormalities in the inner retina of the rd/rd mouse.

We investigated the effects of photoreceptor degeneration on the anatomy and physiology of inner retinal neurons in a mouse model of retinitis pigmentosa, the retinal degeneration (rd) mutant mouse. Although there is a general assumption that the inner retinal cells do not suffer from photoreceptor death, we confirmed major changes both accompanying and after this process. Changes include sprou...

The 3 rd China - Japan